|Nile formed in their hometown of Greenville in 1993. With their self-proclaimed trademark of "Ithyphallic metal", Karl Sanders (guitar/vocals), Chief Spires (bass/vocals), and Pete Hammoura (drums) debuted with their Festivals Of Atonement EP in 1995, leading Nile to a southwestern tour in support of other big metal acts such as Obituary, Deicide, and Broken Hope.
Visceral Productions was responsible for releasing Nile's EP Ramses Bringer Of War in 1997, and was going to release their first album Amongst The Catacombs Of Nephren-Ka, if they had not gone out of business later that year. However, Relapse Records was open to releasing it in early 1998, giving Nile a wider distribution and a chance to hit the road with Incantation and Morbid Angel.
The follow-up, Black Seeds Of Vengeance, was released in late 2000. Prior to this release, Pete Hammoura left the band due to injuries sustained while touring for Amongst The Catacombs Of Nephren-Ka. He tore his rotator cuff and could not recover the use of his arm fully in time to undertake the physical stress of a touring death metal band. He did not want to leave and thought a few more months of rehabilitation could get him up to speed. However, since the band thought he was holding them back, it was agreed that he leave. Derek Roddy drummed on all of the tracks (except "To Dream Of Ur") as a session musician. Also, prior to Black Seeds Of Vengeance, Dallas Toler-Wade joined as a second guitarist/vocalist. A collection of remastered recordings, In The Beginning, was released later the same year.
Chief Spires left the bands a few months after the release of Black Seeds Of Vengeance citing personal and professional differences. He was replaced by Jon Vesano. The band also found a new drummer in Tony Laureano.
By 2002, In Their Darkened Shrines was released. One reviewer noted that the album gave "death metal a cinematic, symphonic twist". Two videos were shot with director Darren Doane, "Sarcophagus" and "Execration Text", respectively.
Annihilation Of The Wicked was released in 2005. New drummer George Kollias stepped in to replace Tony Laureano, who left before the recording began. After recording the bass for Annihilation Of The Wicked, Jon Vesano also left the band. He was temporary replaced by Joe Payne on the following tour. Another Darren Doane directed video was shot for "Sacrifice Unto Sebek".
In May 2006, Nile signed a recording contract with Nuclear Blast. On February 26, 2007, Nile entered the studio and began recording their fifth full-length album entitled Ithyphallic, which was their first release with Nuclear Blast. Karl Sanders had confirmed a release date of June 29 via a posting on the band's message board, which was later pushed back to July 20, 2007. As a special bonus, Nuclear Blast gave several fans the opportunity to listen to the new album two weeks before its release if they could decipher a hieroglyphic message, to which "papyrus" was the answer. Upon the album's release, it sold 4,600 copies, which enabled Nile to get onto the Billboard 200 for the first time, reaching #162 on that chart.
On March 21, 2007, Nile was confirmed as a "Second Stage" act for Ozzfest 2007. A message from Karl Sanders via Nile's MySpace profile indicated that they were excited to finally bring true death metal to an Ozzfest audience. In March/April 2008, Nile went on a US headlining tour with Suicide Silence, The Faceless, Unexpect, and Warbringer. In September/October 2008, Nile set out on a European headlining tour with Grave, Omnium Gatherum and Severe Torture. In October 2008 the band planned to take their Ithyphallic tour to South Africa for a booking of three shows but they were canceled for unknown reasons.
In June 2009, Nile entered the recording studio to begin work on their sixth full-length album, entitled Those Whom The Gods Detest. The album was released in November of the same year, and was critically well-received - with one reviewer suggesting "pretty much the only thing standing in Nile's way at this point is the fact that we as listeners have become so accustomed to the band's excellence that another excellent album seems almost par for the course". It sold 3,500 copies in its first week of release in America, peaking at #160 on the Billboard 200.
On October 21, 2010, Chris Lollis was confirmed as the new permanent bassist for Nile, after four years of session work with the band.
On October 11, 2011, Goomba Music released Worship The Animal, which is a newly titled version of Nile's demo, which the band's original line-up recorded in 1994.
On December 6, 2011, Nile announced work in progress, and the completion of drum tracking, for their upcoming album in 2012. Karl Sanders commented: "We are finished tracking drums for the new Nile album - George, Dallas, Neil Kernon, and I spent a week with Bob Moore at the Soundlab in Columbia SC, tracking drums. We were expecting a long grueling session - some of this material is very compositionally challenging and technically demanding, but George knocked it out, finishing a full week ahead of schedule. Some of the drumming on this record will be boggling people's minds for years to come. At the moment we are back in Greenville, and will commence tracking guitars any day now."
On February 4, 2012, Karl Sanders announced on his Facebook page that they had a new bassist, Todd Ellis, who would contribute vocals to the new record. The next day, he explained on the band's official forum that he had lost contact with Chris Lollis during the writing and recording of the upcoming album, and after three months of silence from him they hired a replacement.